The rabbit monoclonal antibody 1F5 specifically binds to the scFv region of a CD20-specific human monoclonal antibody (mAb, clone 2C6). CD20 (cluster of differentiate 20) is a protein that is expressed on the surface of B cells, starting at the pre-B cell stage and also on mature B cells in the bone marrow and in the periphery. CD20 is not expressed on hematopoietic stem cells, pro-B cells, or normal plasma cells. The scFv region of 2C6 has been used to develop CD20-specific chimeric antigen receptor (CAR) T cells utilized in clinical trials.
| Item Information |
| Catalog # |
202422
|
| Concentration |
2.0 mg/ml
|
| Price |
$3,000.00 |
|
|
| Specification |
| Host Species |
Rabbit |
| Antibody Type |
Monoclonal |
Antibody Format
|
Whole lgG
|
Clone
|
1F5
|
| Excitation (nm) |
650 |
| Reactivity |
Human
|
| Immunogen |
scFv region of a CD20-specific Human mAb clone 2
|
| Storage Buffer |
PBS, pH 7.4
|
Storage Conditions
|
-20°C |
Preparation & Storage
- Store undiluted at -20°C.
- Avoid freeze/thaw cycle of the reagent.
- The monoclonal antibody was purified by Protein A
Application Notes
- Application
- Flow cytometry Routinely Tested
Intellectual Product Notices
- Conditions: The information disclosed herein is not to be construed as a recommendation to use the above product in violation of any patents. BioSwan will not be held responsible for patent infringement or other violations that may occur with the use of our products. Purchase does not include or carry any right to resell or transfer this product either as a stand-alone product or as a component of another product. Any use of this product other than the permitted use without the express written authorization of BioSwan Company is strictly prohibited. For Research Use Only. Not for use in diagnostic or therapeutic procedures. Not for resales.
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