The Benefits of Using Anti-Idiotype Antibodies for CAR Detection in CAR T Therapy
Chimeric Antig en Receptor T-cell (CAR T) therapy has revolutionized the treatment of certain hematological malignancies, offering hope for patients with refractory or relapsed cancers. As the use of CAR […]
Accurate Detection of anti-CD19 CAR-T Cells
Application of R19M, An FMC63 scFv Idiotype Monoclonal Antibody
Anti-CD19 CAR-T cell therapy
With the development of cancer immunotherapy, Chimeric AntigenReceptor (CAR)-T cell, […]
Is CD3ζ alone in CAR structure good enough?
Two CD19-specific CARs approved by US FDA in 2017 have induced prominent responses in patients with refractory leukemia and lymphomas. However, Grade 3/4 CRS and ICANS were reported in proportion […]
