The rabbit polyclonal antibody R19P specifically binds to the scFv region of a CD19-specific mouse monoclonal antibody (mAb, clone FMC63). CD19antigen is a B-cell specific cell surface antigen, which is expressed in all B-cell lineage malignancies and normal B-cells. The scFv region of FMC63hasbeen used to develop CD19-specific chimeric antigen receptor (CAR) T cells utilized in clinical trials.
|Immunogen||scFv region of a CD19-specific mouse mAb clone FMC63|
|Storage buffer||PBS, pH 7.4|
Preparation and Storage
Shipped at 2-8°C. Store at 2-8°C short term (2 weeks). Store at -20°C in small aliquots for long term storage. Avoid freeze/thaw cycle. The polyclonal antibody was purified by Protein A.
- Since applications vary, each investigatorshould titrate the reagent to obtain optimal results.
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